FTO, human recombinant

The gene responsible for mouse ‘fused toes’ mutation.
Catalog #: 7557 | abID: ab109039

Product Details

abID ab109039
Cat # +Size 7557-10
Size 10 μg
Alternate Name Fat Mass and Obesity-associated Protein; FATSO.
Gene Symbol FTO
Gene ID 79068
Accession # Q9C0B1
Source E. coli
Appearance Liquid
Physical Form Description In 0.2 μm-filtered solution in 55 mM Tris-Cl, pH 8.2 containing 150 mM NaCl.
Molecular Weight ~65 kDa (SDS-PAGE). Human FTO (aa 2-505) is fused at the N-terminus to a His-tag.
Purity by SDS-PAGE ≥90%
Endotoxin Level <1 EU/μg by LAL method
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.


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