Fructose 1,6-bisphophatase 1, Active, Human Recombinant

A full length, active Fructose 1,6-bisphophatase 1 acting as the rate-limiting step during gluconeogenesis.
Catalog #: P1269 | abID: ab286057

Product Details

abID ab286057
Alternate Name FBP1, FBP, FBPase 1, Liver FBPase
Gene Symbol FBP1
Gene ID 2203
Accession # P09467
Source E. coli
Physical Form Description Lyophilized powder from 0.22 μm filtered solution in PBS containing 8% trehalose
Purity by SDS-PAGE ≥90%
Purity by Lyophilized protein
Endotoxin Level Lyophilized protein
Biological Activity One unit is the amount of enzyme that will hydrolyze 1.0 µmole of fructose 1,6-bisphosphate to fructose 6-phosphate at pH 8.0 and 37 ̊C for 30 minutes.
Reconstitution Instructions Reconstitute in deionized water to a final concentration of 1.5 µg/ml.
Handling Centrifuge the vial prior to opening.
Storage Conditions -70°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


The conversion of fructose 1,6-bisphosphate to fructose 6 phosphate by fructose 1,6-bisphosphatase is the rate-limiting step during gluconeogenesis. The enzyme plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells and modulates glycerol gluconeogenesis in liver. It is involved in regulation of adiposity and appetite.

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