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A HMG-CoA reductase inhibitor
Catalog #: B2366

In stock

SKU-Size Size Price Qty
B2366-10 10 mg
B2366-50 50 mg
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Product Details

Alternate Name 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid
Appearance Off-white to yellow solid
CAS # 93957-54-1
Molecular Formula C₂₄H₂₆FNO₄
Molecular Weight 411.47
Purity ≥98%
Solubility ~14 mg/ml (DMSO)
InChi InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19-/m1/s1
PubChem CID 446155
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Fluvastatin is a potent and selective HMG-CoA reductase inhibitor. It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits increases in serum cholesterol, triglycerides, phospholipids, and thiobarbituric acid-reactive substances (TBARS) levels, as well as vascular angiotensin converting enzyme (ACE) activity in rabbits fed a high-cholesterol diet.

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