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Fluvastatin sodium

A HMG-CoA reductase inhibitor
Catalog #: B2367

In stock

SKU-Size Size Price Qty
B2367-10 10 mg
$65.00
B2367-50 50 mg
$255.00
More Sizes Get Quote

Product Details

Alternate Name 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, sodium salt
Appearance Pale yellow solid
CAS # 93957-55-2
Molecular Formula C₂₄H₂₅FNNaO₄
Molecular Weight 433.45
Purity ≥98%
Solubility >10 mg/ml (DMSO)
SMILES CC(C)N1C2=CC=CC=C2C(=C1C=CC(CC(CC(=O)[O-])O)O)C3=CC=C(C=C3)F.[Na+]
InChi InChI=1S/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/q;+1/p-1/b12-11+;/t18-,19-;/m1./s1
InChi Key ZGGHKIMDNBDHJB-NRFPMOEYSA-M
PubChem CID 23663976
MDL Number MFCD08063391
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Fluvastatin sodium is a potent and selective HMG-CoA reductase inhibitor. It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits increases in serum cholesterol, triglycerides, phospholipids, and thiobarbituric acid-reactive substances (TBARS) levels, as well as vascular angiotensin converting enzyme (ACE) activity in rabbits fed a high-cholesterol diet.


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