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Product Details
| Alternate Name | NSC 103805 5-Fluorocytosine 6-amino-5-fluoro-2(1H)-pyrimidinone 5-FC |
|---|---|
| Peptide Sequence | N/A |
| Appearance | White to off-white solid |
| CAS # | 2022-85-7 |
| Molecular Formula | C₄H₄FN₃O |
| Molecular Weight | 129.09 |
| Purity | ≥98% by HPLC |
| Solubility | ~0.2 mg/ml DMSO |
| SMILES | C1=NC(=O)NC(=C1F)N |
| InChi | InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9) |
| InChi Key | XRECTZIEBJDKEO-UHFFFAOYSA-N |
| PubChem CID | 3366 |
| MDL Number | MFCD00006035 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Flucytosine, a fluorinated pyrimidine analog that displays antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. Flucytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.
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