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FKBP12 Antibody

Catalog #: 3635
SKU-Size Size Price Qty
3635-30T 30 µg
$89.00
3635-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target FKBP 12
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 10 of mouse FKBP12
Accession # P26883
Gene ID 14225
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot, Immunohistochemistry/Immunoprecipitation
Application & Usage Western blot (0.5-4 µg/ml), immunoprecipitation (2-10 µg/ml) and Immunohistochemistry (2-10 µg/ml). However, the optimal conditions should be determined individually. The antibody detects 12 kDa FKBP12 protein in samples from human, mouse, and rat origins
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.


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