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A caspase-2 in situ marker
Catalog #: 9498

Product Details

Cat # +Size 9498-100
Size 100 assays
Alternate Name FITC-Val-Asp-Val-Ala-Asp-fluoromethyl ketone; FITC-VD(OMe)-VAD(OMe)-FMK
Peptide Sequence FITC-VD(OMe)-VAD(OMe)-FMK
Appearance Liquid
Formulation A 0.6 mM solution in DMSO
Molecular Formula C₄₅H₅₁FN₆O₁₄S
Molecular Weight 950.98
Purity ≥98% by HPLC
SMILES O=C(OC)C[[email protected]](NC([[email protected]@H](NC([[email protected]@H](NC([[email protected]@H](NC([[email protected]@H](N/C(S)=N/C1=CC=C(C2(C3=CC=C(O)C=C3OC4=C2C=CC(O)=C4)OC5=O)C5=C1)C(C)C)=O)CC(OC)=O)=O)C(C)C)=O)C)=O)C(CF)=O
InChi InChI=1S/C45H51FN6O14S/c1-20(2)37(41(60)47-22(5)39(58)49-30(32(55)19-46)17-35(56)63-6)51-40(59)31(18-36(57)64-7)50-42(61)38(21(3)4)52-44(67)48-23-8-11-27-26(14-23)43(62)66-45(27)28-12-9-24(53)15-33(28)65-34-16-25(54)10-13-29(34)45/h8-16,20-22,30-31,37-38,53-54H,17-19H2,1-7H3,(H,47,60)(H,49,58)(H,50,61)(H,51,59)(H2,48,52,67)/t22-,30-,31-,37-,38-/m0/s1
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


FITC-VD(OMe)VAD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase-2 inhibitor VD(OMe)VAD(OMe)-FMK that acts as an in situ marker for detection of caspase-2 in • Living cells. FITC-VD(OMe)VAD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-2 in apoptotic cells. The bound marker is localized by fluorescence detection.

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