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FITC-IETD-FMK

A caspase-8 in situ marker
Catalog #: 9533
$285.00

Product Details

Cat # +Size 9533-100
Size 100 assays
Alternate Name FITC-Ile-Glu-Thr-Asp-fluoromethyl ketone; FITC-I-E(OMe)-TD(OMe)-FMK
Peptide Sequence FITC-I-E(OMe)-TD(OMe)-FMK
Appearance Liquid
Formulation A 0.6 mM solution in DMSO
Molecular Formula C₄₃H₄₈FN₅O₁₄S
Molecular Weight 909.93
Purity ≥98% by HPLC
SMILES S/C(N[[email protected]@H]([[email protected]@H](C)CC)C(N[[email protected]](C(N[[email protected]@H]([[email protected]](O)C)C(N[[email protected]](C(CF)=O)CC(OC)=O)=O)=O)CCC(OC)=O)=O)=N\C1=CC=C(C2(C3=CC=C(O)C=C3OC4=C2C=CC(O)=C4)OC5=O)C5=C1
InChi InChI=1S/C43H48FN5O14S/c1-6-20(2)36(39(57)46-29(13-14-34(54)60-4)38(56)48-37(21(3)50)40(58)47-30(31(53)19-44)18-35(55)61-5)49-42(64)45-22-7-10-26-25(15-22)41(59)63-43(26)27-11-8-23(51)16-32(27)62-33-17-24(52)9-12-28(33)43/h7-12,15-17,20-21,29-30,36-37,50-52H,6,13-14,18-19H2,1-5H3,(H,46,57)(H,47,58)(H,48,56)(H2,45,49,64)/t20-,21+,29-,30-,36-,37-/m0/s1
InChi Key ZQSUFEPGEWYBEF-NINMPSEZSA-N
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

FITC-IE(OMe)TD(OMe)-FMK is a fluorescein isothiocyanate (FITC) conjugate of the cell- permeable caspase-8 inhibitor IE(OMe)TD(OMe)-FMK that acts as an in situ marker for detection of caspase-8 in • Living cells. FITC-IE(OMe)TD(OMe)-FMK is nontoxic, and irreversibly binds to activated caspase-8 in apoptotic cells. The bound marker is localized by fluorescence detection.


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