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Filastatin

A nontoxic inhibitor of adhesion to human cells
Catalog #: B2767
SKU-Size Size Price Qty
B2767-5 5 mg
$85.00
B2767-25 25 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name (3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone
Peptide Sequence N/A
Appearance White to off-white solid
CAS # 431996-53-1
Molecular Formula C₁₈H₁₈ClN₃O₃
Molecular Weight 359.81
Purity ≥98%
Solubility ~15 mg/ml DMSO
SMILES O=C(C1=CC=C(C)C(Cl)=C1)N2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2
InChi InChI=1S/C18H18ClN3O3/c1-13-2-3-14(12-17(13)19)18(23)21-10-8-20(9-11-21)15-4-6-16(7-5-15)22(24)25/h2-7,12H,8-11H2,1H3
InChi Key PNECWWUOUHGWQG-UHFFFAOYSA-N
PubChem CID 2911546
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Filastatin is a nontoxic inhibitor of adhesion to human cells. Filastatin blocks the ability of Candida albicans, and other Candida sp. to bind to polystyrene, and human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1.


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