A Wnt pathway antagonist
Catalog #: 2657 | abID:

Product Details

Alternate Name 2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide
Appearance Off-white solid
CAS # 108409-83-2
Molecular Formula C₁₃H₁₀Cl₂N₂O₄S
Molecular Weight 361.2
Purity ≥98% by HPLC
Solubility DMSO (~25 mg/ml)
SMILES CC1=C(C=CC(=C1)[N+](=O)[O-])NS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl
InChi InChI=1S/C13H10Cl2N2O4S/c1-8-6-10(17(18)19)3-5-12(8)16-22(20,21)13-7-9(14)2-4-11(13)15/h2-7,16H,1H3
PubChem CID 3463933
MDL Number MFCD01212888
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


FH535 is a potent, reversible dual inhibitor of Wnt/β-catenin and a PPARγ and PPARδ signaling. FH535 antagonizes both PPARg and PPARδ ligand-dependent activation and shows structural similarity to GW9662, a known PPARgamma antagonist. The compound is selectively toxic to some carcinomas expressing the Wnt/β-catenin pathway.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.