Product Details
| Alternate Name | N-(4-Hydroxyphenyl)retinamide; 4-HPR; MK-4016; Ro 22-4667 |
|---|---|
| Appearance | Yellow solid |
| CAS # | 65646-68-6 |
| Molecular Formula | C₂₆H₃₃NO₂ |
| Molecular Weight | 391.55 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (>30 mg/ml) or EtOH (>30 mg/ml) |
| SMILES | CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)NC2=CC=C(C=C2)O)C)C |
| InChi | InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+ |
| InChi Key | AKJHMTWEGVYYSE-FXILSDISSA-N |
| PubChem CID | 5288209 |
| MDL Number | MFCD00792674 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Fenretinide is a Vitamin A acid analog that displays antioxidant and antiproliferative activity. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types.
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