Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]



A FTO inhibitor
Catalog #: B2740
SKU-Size Size Price Qty
B2740-1 1 mg
B2740-5 5 mg
More Sizes Get Quote

Product Details

Alternate Name FB-232; 2-((2,6-dichloro-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)-N-hydroxybenzamide; FTO inhibitor
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 2243736-45-8
Molecular Formula C₁₈H₁₅Cl₂N₃O₃
Molecular Weight 392.24
Purity ≥98%
Solubility >50 mg/ml DMSO
InChi InChI=1S/C18H15Cl2N3O3/c1-9-16(10(2)26-23-9)11-7-13(19)17(14(20)8-11)21-15-6-4-3-5-12(15)18(24)22-25/h3-8,21,25H,1-2H3,(H,22,24)
PubChem CID 138454779
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


FB23-2 is a potent FTO (fat mass and obesity-associated) inhibitor. FB23-2 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity (IC50 = 2.6 µM). Mimicking FTO depletion, FB23-2 dramatically suppresses proliferation and promotes the differentiation/apoptosis of human acute myeloid leukemia (AML) cell line cells and primary blast AML cells in vitro.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.