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Fas Ligand Antibody (Clone I-6060)

based on 1 citations in multiple journalsFas Ligand Antibody (Clone I-6060)14.1 4
Catalog #: 3330
$295.00

Product Details

Cat # +Size 3330-100
Size 100 µg
Antibody Target FasL
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG1
Immunogen Recombinant human Fas Ligand
Accession # P48023
Gene ID 356
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) Protein G purified mouse monoclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Purification Affinity purified
Species Reactivity Human
Application Western blot, Immunoprecipitation, Immunohistochemistry
Application & Usage Western blotting (1-4 µg/ml), immunoprecipitation, and Immunohistochemistry. However, the optimal conditions should be determined individually. HeLa cell lysate can be used as a positive control and an approximately 40 kDa band should be detected by Weste
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or Fas ligand (FasL). FasL is a tumor necrosis factor (TNF)-related type II membrane protein and is expressed in various tissue and cells. Both Fas and FasL are thoμght to play an important role in the apoptosis processes that takes place during T cell development.


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Dakhova O et al (2008) Endocrinology 10.1210/en.2008-0673.
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