EZSolution™ Stat3 Inhibitor I, S3I-201

A Stat3 Inhibitor
Catalog #: 2541 | abID: ab146606

Product Details

abID ab146606
Cat # +Size 2541-5
Size 5 mg
Alternate Name 2-Hydroxy-4-[[[[4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid; NSC 74859; S3I-201
Appearance Liquid
Formulation A 10 mM solution in anhydrous DMSO
CAS # 501919-59-1
Molecular Formula C₁₆H₁₅NO₇S
Molecular Weight 365.36
Purity ≥97% by HPLC
InChi InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)
PubChem CID 252682
MDL Number MFCD09907564
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC₅₀ = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin and inhibits the growth of human breast tumors in vivo.

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