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Product Details
| Cat # +Size | 1748-5 |
|---|---|
| Size | 5 mg |
| Alternate Name | 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile; CT99021 |
| Appearance | Liquid |
| Formulation | 10 mM (DMSO) |
| CAS # | 252917-06-9 |
| Molecular Formula | C₂₂H₁₈Cl₂N₈ |
| Molecular Weight | 465.34 |
| Purity | ≥98% by HPLC |
| SMILES | CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N |
| InChi | InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32) |
| InChi Key | AQGNHMOJWBZFQQ-UHFFFAOYSA-N |
| PubChem CID | 9956119 |
| MDL Number | MFCD12546133 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A 10 mM (5 mg in 1075 µl) solution of CHIR99021 (Cat. No. 1677-5) in anhydrous DMSO.
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Khan et al., Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Mol. Cell. Biol., Sep 2015; 35: 3029 - 3043.
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