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EZSolution™ CHIR99021, Sterile-Filtered

A potent GSK-3β inhibitor
Catalog #: 1991
$250.00

Product Details

Cat # +Size 1991-1
Size 1 ml
Alternate Name 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile; CT99021
Appearance Liquid
Formulation A 10 mM sterile-filtered solution in DMSO
CAS # 252917-06-9
Molecular Formula C₂₂H₁₈Cl₂N₈
Molecular Weight 465.34
Purity ≥95% by HPLC
SMILES CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N
InChi InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32)
InChi Key AQGNHMOJWBZFQQ-UHFFFAOYSA-N
PubChem CID 9956119
MDL Number MFCD12546133
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A 10 mM (4.65 mg in 1 ml), sterile-filtered solution of the GSK-3β inhibitor CHIR99021 (Cat. No. 1677) in anhydrous DMSO.


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Disi An, Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons. eLife, June 2019; 31157617.
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