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EZSolution™ 5-Fluoroorotic acid monohydrate (5-FOA)

A solution (100 mg/ml) of 5-fluoroorotic acid (5-FOA) (Cat.No. 2796) in anhydrous DMSO.
Catalog #: 2797
$125.00

Product Details

Cat # +Size 2797-10
Size 10 ml
Alternate Name 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid hydrate
Appearance Liquid
Formulation In DMSO (100 mg/ml)
CAS # 703-95-7, 207291-81-4, 220141-70-8
Molecular Formula C₅H₃FN₂O₄.H₂O
Molecular Weight 192.1
Purity ≥97% by titration
SMILES C1(=C(NC(=O)NC1=O)C(=O)O)F.O
InChi InChI=1S/C5H3FN2O4.H2O/c6-1-2(4(10)11)7-5(12)8-3(1)9;/h(H,10,11)(H2,7,8,9,12);1H2
InChi Key LODRRYMGPWQCTR-UHFFFAOYSA-N
PubChem CID 16212749
MDL Number MFCD00150658
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

5-Fluoroorotic Acid (5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) decarboxylase. 5-FOA is toxic to yeast cells that can synthesize the enzyme orotidine-5’-phosphate decarboxylase and are therefore unable to grow in 5-FOA-containing media.


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