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EZSolution ™ Dalcetrapib

A CETP inhibitor
Catalog #: 2532

In stock

$85.00

Product Details

Cat # +Size 2532-1
Size 1 mg
Alternate Name S-2-(1-(2-ethylbutyl)cyclohexanecarboxamido)phenyl 2-methylpropanethioate; JTT-705; RO4607381
Appearance Liquid
Formulation A 10 mM solution in anhydrous DMSO
CAS # 211513-37-0
Molecular Formula C₂₃H₃₅NO₂S
Molecular Weight 389.59
Purity ≥98%
SMILES CCC(CC)CC1(CCCCC1)C(=O)NC2=CC=CC=C2SC(=O)C(C)C
InChi InChI=1S/C23H35NO2S/c1-5-18(6-2)16-23(14-10-7-11-15-23)22(26)24-19-12-8-9-13-20(19)27-21(25)17(3)4/h8-9,12-13,17-18H,5-7,10-11,14-16H2,1-4H3,(H,24,26)
InChi Key YZQLWPMZQVHJED-UHFFFAOYSA-N
PubChem CID 6918540
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Dalcetrapib is a potent CETP modulator. It is a thioester pro-drug that is rapidly hydrolyzed to generate a pharmacologically active thiol. Dalcetrapib modulates cholesteryl ester transfer protein (CETP) activity to raise high-density lipoprotein cholesterol (HDL-C). It achieves 50% inhibition of CETP activity in human plasma at a concentration of 9 μM.


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