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Exodus-2, Mouse Recombinant

A chemokine which inhibits hemopoiesis and stimulates chemotaxis
Catalog #: 7681

In stock

SKU-Size Size Price Qty
7681-20 20 μg
$245.00
7681-100 100 μg
$775.00
7681-1000 1 mg
$3,835.00
More Sizes Get Quote

Product Details

Alternate Name C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21
Gene Symbol CCL21
Gene ID 18829
Accession # P84444
Source E. coli
Appearance Lyophilized powder
Physical Form Description Lyophilized powder. Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL
Molecular Weight 12 kDa
Purity by SDS-PAGE ≥98%
Endotoxin Level ≤ 1 EU/μg protein
Biological Activity The activity is determined by its ability to chemoattract 5-10 day old cultures of human peripheral blood lymphocytes at concentrations between 200 ng/mL- 600 ng/mL.
Reconstitution Instructions Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL
Amino Acid Sequence SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Exodus-2, also known as CCL21 and 6Ckine, is a novel chemokine produced at high levels in human lymph node tissue and the spleen. 6Ckine signals through the CCR7 receptor to recruit thymocytes and activated T cells in vitro, but is not known to be chemotactic for monocytes. Human and mouse Exodus-2 share > 85% amino acid homology. Recombinant mouse Exodus-2 is a nonglycosylated protein, containing 110 amino acids, with a molecular weight of 12 kDa.


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