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A potent and selective CETP inhibitor
Catalog #: 2558
SKU-Size Size Price Qty
2558-5 5 mg
2558-25 25 mg
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Product Details

Alternate Name trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl]methyl]- cyclohexanecarboxylic acid; LY2484595
Appearance Crystalline solid
CAS # 1186486-62-3
Molecular Formula C₃₁H₃₆F₆N₆O₂
Molecular Weight 638.65
Purity ≥95% by HPLC
Solubility DMSO (>10 mg/ml)
InChi InChI=1S/C31H36F6N6O2/c1-18-11-19(2)27-25(12-18)26(5-4-10-42(27)16-20-6-8-22(9-7-20)28(44)45)43(29-38-40-41(3)39-29)17-21-13-23(30(32,33)34)15-24(14-21)31(35,36)37/h11-15,20,22,26H,4-10,16-17H2,1-3H3,(H,44,45)/t20?,22?,26-/m0/s1
PubChem CID 49836058
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Evacetrapib is a potent, and selective CETP (cholesteryl ester transfer protein) inhibitor. It inhibits human recombinant CETP protein (IC₅₀ = 5.5 nM ) and CETP activity in human plasma (IC₅₀ = 36 nM) in vitro. Unlike Torcetrapib (Cat. No. 2420 & 2533), Evacetrapib does not induce aldosterone or cortisol biosynthesis.

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