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EUK-134

based on 1 citations in multiple journalsEUK-13414.1 4
A synthetic superoxide dismutase (SOD)/catalase mimetic
Catalog #: 2175
SKU-Size Size Price Qty
2175-5 5 mg
$55.00
2175-25 25 mg
$195.00
More Sizes Get Quote

Product Details

Alternate Name chloro[[2,​2'-​[1,​2-​ethanediylbis[(nitrilo-​κN)methylidyne]]bis[6-​methoxyphenolato-​κO]]]-​manganese
Appearance Off-white solid
CAS # 81065-76-1
Molecular Formula C₁₈H₁₈ClMnN₂O₄
Molecular Weight 416.74
Purity ≥98%
Solubility DMSO (~ 20 mg/ml)
SMILES COC1=CC=CC(=C1[O-])C=NCCN=CC2=C(C(=CC=C2)OC)[O-].[Cl-].[Mn+2]
InChi InChI=1S/C18H20N2O4.ClH.Mn/c1-23-15-7-3-5-13(17(15)21)11-19-9-10-20-12-14-6-4-8-16(24-2)18(14)22;;/h3-8,11-12,21-22H,9-10H2,1-2H3;1H;/q;;+2/p-3
InChi Key ZCNKLAVGNJEDNF-UHFFFAOYSA-K
PubChem CID 45489809
MDL Number MFCD08059577
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A synthetic superoxide dismutase (SOD)/catalase mimetic. EUK 134 is a salen-manganese complex that has been modified to increase its catalase activity while retaining SOD activity.


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Wang et al., Protein kinase D1 is essential for Ras-induced senescence and tumor suppression by regulating senescence-associated inflammation. PNAS, May 2014; 111: 7683 - 7688.
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