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Etalocib

An orally active leukotriene B4 receptor antagonist
Catalog #: B3376
SKU-Size Size Price Qty
B3376-1 1 mg
$85.00
B3376-5 5 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name LY293111 2-(3-(3-((5-ethyl-4'-fluoro-2-hydroxy-[1,1'-biphenyl]-4-yl)oxy)propoxy)-2-propylphenoxy)benzoate sodium VML 295
Appearance Solid
CAS # 161172-51-6
Molecular Formula C₃₃H₃₂FNaO₆
Molecular Weight 566.59
Purity ≥98%
Solubility >50 mg/ml DMSO
SMILES CCCC1=C(C=CC=C1OC2=CC=CC=C2C(=O)O)OCCCOC3=CC(=C(C=C3CC)C4=CC=C(C=C4)F)O
InChi InChI=1S/C33H33FO6/c1-3-9-25-29(12-7-13-30(25)40-31-11-6-5-10-26(31)33(36)37)38-18-8-19-39-32-21-28(35)27(20-22(32)4-2)23-14-16-24(34)17-15-23/h5-7,10-17,20-21,35H,3-4,8-9,18-19H2,1-2H3,(H,36,37)
InChi Key YFIZRWPXUYFCSN-UHFFFAOYSA-N
PubChem CID 177941
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Etalocib (LY293111) is a potent and selective inhibitor of the lipoxygenase pathway either directly through 5'-lipoxygenase or via antagonism of the leukotriene B4 (LTB4) receptor. Etalocib (LY293111) prevents LTB4-induced calcium mobilization with an lC50 of 20 nM. LY293111 has antineoplastic activity in a variety of preclinical models.


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