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Erk5 Antibody

Catalog #: 3397
$265.00

Product Details

Cat # +Size 3397-100
Size 100 µg
Antibody Target Erk5
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide from human Erk5
Accession # Q13164.2
Gene ID 205371766
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~115 kDa Erk5 of human, mouse, and rat origins.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Erk-5 shares high homology in the amino-terminal kinase domain with Erk1/2. However, the long carboxy-terminal kinase domain makes Erk5 a unique MAP kinase. Erk5 is activated by a variety of extracellular signals. The direct upstream kinase of Erk5 is defined as MEK5. Studies show that Erk5 pathway is involved in proliferation, differentiation, oncogenesis, and development.


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