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Epothilone D

A microtubule stabilizing agent
Catalog #: 9559
SKU-Size Size Price Qty
9559-1 1 mg
$175.00
9559-5 5 mg
$695.00
More Sizes Get Quote

Product Details

Alternate Name (4S,7R,8S,9S,16S,Z)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)oxacyclohexadec-13-ene-2,6-dione; (-)-Desoxyepothilone B; (-)-Epothilone D; 12,13-Deoxyepothilone B; 12,13-Desoxyepothilone B; Desoxyepothilone B; Epo D; Epothilone D; KOS 862; KOS862; KOS-862; NSC 703147
Appearance Crystalline solid
CAS # 189453-10-9
Molecular Formula C₂₇H₄₁NO₅S
Molecular Weight 491.68
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml)
SMILES CC1CCCC(=CCC(OC(=O)CC(C(C(=O)C(C1O)C)(C)C)O)C(=CC2=CSC(=N2)C)C)C
InChi InChI=1S/C27H41NO5S/c1-16-9-8-10-17(2)25(31)19(4)26(32)27(6,7)23(29)14-24(30)33-22(12-11-16)18(3)13-21-15-34-20(5)28-21/h11,13,15,17,19,22-23,25,29,31H,8-10,12,14H2,1-7H3/b16-11-,18-13+/t17-,19+,22-,23-,25-/m0/s1
InChi Key XOZIUKBZLSUILX-GIQCAXHBSA-N
PubChem CID 447865
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Epothilone D is a natural polyketide compound isolated from the myxobacterium Sorangium cellulosum. Epothilone D binds to tubulin and inhibits the disassembly of microtubules, resulting in the inhibition of mitosis, cellular proliferation, and cell motility.


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