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(-)-Epigallocatechin gallate

An antioxidant
Catalog #: 1841
$95.00

Product Details

Cat # +Size 1841-50
Size 50 mg
Alternate Name EGCG; (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate)
Appearance Off-white to yellow solid
CAS # 989-51-5
Molecular Formula C₂₂H₁₈O₁₁
Molecular Weight 458.37
Purity ≥98% by HPLC
Solubility DMSO or EtOH
SMILES C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
InChi InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
InChi Key WMBWREPUVVBILR-WIYYLYMNSA-N
PubChem CID 65064
MDL Number MFCD00075940
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A polyphenol flavonoid that displays antitumor and antioxidant properties. Inhibits telomerase and DNA methyltransferase (DNMT) and blocks the activation of EGF receptors and HER-2 receptors. Also potently and specifically inhibits chymotrypsin-like activity of the proteasome in vitro (IC₅₀= 86-194 nM) and in vivo (IC₅₀ =1 -10 µM).


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