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An aldose reductase inhibitor
Catalog #: 2397
SKU-Size Size Price Qty
2397-5 5 mg
2397-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 2-[(5Z)-5-[(E)-3-phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid
Appearance Yellow solid
CAS # 82159-09-9
Molecular Formula C₁₅H₁₃NO₃S₂
Molecular Weight 319.4
Purity ≥98% by TLC
Solubility DMSO (~5 mg/ml)
InChi InChI=1S/C15H13NO3S2/c1-10(7-11-5-3-2-4-6-11)8-12-14(19)16(9-13(17)18)15(20)21-12/h2-8H,9H2,1H3,(H,17,18)/b10-7+,12-8-
PubChem CID 1549120
Handling Protect from light and air
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Epalrestat is an aldose reductase inhibitor (IC₅₀ = 10 nM (rat lens) and 25 nM (human placenta). It reduces sorbitol accumulation in the sciatic nerve, erythrocytes and ocular tissue. May be used to prevent or slow the progression of diabetic neuropathy.

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