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Eotaxin/CCL11, human recombinant

A chemokine characterized by its high chemotactic selectivity for eosinophils
Catalog #: 4028
SKU-Size Size Price Qty
4028-20 20 μg
$190.00
4028-100 100 μg
$665.00
4028-1000 1 mg
$3,250.00
More Sizes Get Quote

Product Details

Alternate Name Eotaxin, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11
Gene Symbol CCL-11
Gene ID 6356
Accession # P51671
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized from 20 mM phosphate buffer (pH 7.4) and 150 mM NaCl.
Molecular Weight 8.3 kDa
Purity by SDS-PAGE ≥97%
Purity by ≥97%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ of human Eotaxin by chemotaxis based assays is 10 ng/ml using human peripheral blood eosinophils.
Reconstitution Instructions The lyophilized Eotaxin can be reconstituted in water to a concentration of 0.1-1 µg/µl. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Eotaxin is a recently discovered chemokine characterized by its high chemotactic selectivity for eosinophils. The position of the four cystein residues in Eotaxin places it in the C-C family of chemokines, along with chemokines such as RANTES, MCP-3, and MIP-1 alpha. The human Eotaxin is an 8.3 kDa protein containing 74 amino acid residues. The sequence of the first five N-terminal amino acids is Gly-Pro-Ala-Ser-Val.


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