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eNOS Antibody

Catalog #: 3426R
SKU-Size Size Price Qty
3426R-30T 30 µg
$89.00
3426R-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target eNOS
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 602 of rat eNOS
Accession # EDL99377
Gene ID 24600
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes 140 kDa eNOS of human, mouse, and rat origins. Reactivity to other species has not been tested.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

eNOS (Endothelial nitric-oxide synthase) is an important enzyme in the cardiovascular system. eNOS is regulated by phosphorylation at multiple sites. The two most thoroμghly studied sites are the activation site Ser1177 and the inhibitory site Thr495. Several protein kinases including Akt/PKB, PKA and AMPK activate eNOS by phosphorylating Ser1177 in response to various stimuli. In contrast, bradykinin and hydrogen peroxide activate eNOS activity by promoting Thr495 dephosphorylation.


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