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A selective inhibitor of Aurora A and Flt3
Catalog #: B1938

In stock

SKU-Size Size Price Qty
B1938-5 5 mg
B1938-25 25 mg
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Product Details

Alternate Name 6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]pyrimidin-4-amine
Appearance Crystalline solid
CAS # 934353-76-1
Molecular Formula C₂₁H₂₅N₇
Molecular Weight 375.47
Purity ≥98% by HPLC
Solubility DMSO (~ 18 mg/ml)
InChi InChI=1S/C21H25N7/c1-16-14-20(26-25-16)23-19-15-21(28-12-10-27(2)11-13-28)24-18(22-19)9-8-17-6-4-3-5-7-17/h3-9,14-15H,10-13H2,1-2H3,(H2,22,23,24,25,26)/b9-8+
PubChem CID 16041424
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


ENMD-2076 is a selective inhibitor of Aurora A and Flt3 with IC₅₀ values of 14 and 1.86 nM, respectively. Displays 5-fold selectivity for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα.

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