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Enhanced Apoptotic DNA Ladder Detection Kit

based on 7 citations in multiple journalsEnhanced Apoptotic DNA Ladder Detection Kit74.2 4
Detects Apoptotic DNA within 90 min., Highly Sensitive
Catalog #: K130
$345.00

Product Details

Cat # +Size K130-50
Size 50 assays
Detection Method Agarose gel electrophoresis
Species Reactivity Mammalian
Applications Detects efficiently DNA fragmentation from apoptotic cells
Features & Benefits • Simple one-step procedure; takes only 90 minutes
• Fast and convenient
• Higher sensitivity in comparison to other similar kits in the market. The assay can be used to detect apoptotic DNA ladder in both tissues and cells.
Kit Components • TE Lysis Buffer
• Enzyme B (Lyophilized)
• Ammonium Acetate Solution
• DNA Suspension Buffer
• Staining Dye (10000X)
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Internucleosomal DNA fragmentation is a hallmark of apoptosis in mammalian cells. BioVision’s Enhanced Apoptotic DNA Ladder Detection Kit provides an easy and sensitive means for detecting DNA fragmentation in apoptotic cells. Unlike other commercially available kits that require 1-2 days to perform the procedure, the new detection method requires less than 90 minutes to prepare DNA, with neither extraction nor using columns. DNA fragmentation can be easily visualized by agarose gel electrophoreses stained with a highly sensitive dye.


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WOO HYUN PAIK et al., Chemosensitivity Induced by Down-regulation of MicroRNA-21 in Gemcitabine-resistant Pancreatic Cancer Cells by Indole-3-Carbinol. Anticancer Res, Apr 2013; 33: 1473 - 1481.
Wong, C.K. et al.  Thymic Stromal Lymphopoietin Induces Chemotactic and Prosurvival Effects in Eosinophils: Implications in Allergic Inflammation.Am. J. Respir. Cell Mol. Biol., Sep 2010; 43: 305 - 315.
Wang L et al (2008) Cancer Res. 68: 4377-4383.
Papineni S et al. (2008) Mol. Pharmacol. 73: 553 - 565.
Kang SG et al. (2007) J. Biol. Chem. 282: 6090-6097.
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