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Endostatin Antibody

Catalog #: 5799
SKU-Size Size Price Qty
5799-30T 30 µg
$89.00
5799-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target Endostatin
Alternate Name Endostatin Polyclonal Ab, Endostatin antibody, Endostatin, Anti-Endostatin
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen E. coli-expressed recombinant human Endostatin
Accession # P39059
Gene ID 1306
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 30 µg (0.5 mg/ml) affinity purified rabbit anti-human Endostatin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human
Application Western blot
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Endostatin has been identified as a C-terminal fragment of Collagen type 18, a recently identified member of a family of collagen-like proteins referred to as multiplexin family Endostatin specifically inhibits proliferation of endothelial cells althoμgh it does not affect the proliferation of EOMA cells. Endostatin also potently inhibits angiogenesis and tumor growth. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes. Recombinant Endosatin expressed in yeast causes G1 arrest of endothelial cells, and endostatin treatment results in apoptosis of HUVE and HMVE cells.


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