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Elvitegravir

A HIV-1 integrase inhibitor
Catalog #: 9465
SKU-Size Size Price Qty
9465-5 5 mg
$115.00
9465-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name 6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; EVG, JTK-303/GS-9137
Appearance White solid
CAS # 697761-98-1
Molecular Formula C₂₃H₂₃ClFNO₅
Molecular Weight 447.88
Purity ≥98% by HPLC
Solubility DMSO (>50 mg/ml)
SMILES CC(C)C(CO)N1C=C(C(=O)C2=CC(=C(C=C21)OC)CC3=C(C(=CC=C3)Cl)F)C(=O)O
InChi InChI=1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6,8-10,12,19,27H,7,11H2,1-3H3,(H,29,30)/t19-/m1/s1
InChi Key JUZYLCPPVHEVSV-LJQANCHMSA-N
PubChem CID 5277135
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Elvitegravir is a novel HIV-1 integrase inhibitor that blocks strand transfer by the viral enzyme. It displays an IC₅₀ of 7.2 nM in the strand transfer assay, and shows an EC₅₀ of 0.9 nM in an acute HIV-1 infection assay.


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