A potent P-glycoprotein (P-gp/ABCG1) and breast cancer resistance protein (BCRP) inhibitor
Catalog #: 2792 | abID:

Product Details

Alternate Name N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide;GF120918; GG 918; GW0918; GF-120918)
Appearance Yellow solid
CAS # 143664-11-3
Molecular Formula C₃₄H₃₃N₃O₅
Molecular Weight 563.64
Purity ≥98% by HPLC
Solubility DMSO (~ 2 mg/ml)
InChi InChI=1S/C34H33N3O5/c1-40-28-9-5-7-26-32(28)36-31-25(33(26)38)6-4-8-27(31)34(39)35-24-12-10-21(11-13-24)14-16-37-17-15-22-18-29(41-2)30(42-3)19-23(22)20-37/h4-13,18-19H,14-17,20H2,1-3H3,(H,35,39)(H,36,38)
PubChem CID 119373
MDL Number MFCD00912604
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Elacridar is a potent P-glycoprotein (P-gp/ABCG1) and breast cancer resistance protein (BCRP) inhibitor . GF120918 increases the bioavailability of cytotoxic anti-tumor drugs, and also leads to increased levels of anti-HIV drugs in the brain and CNS.

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