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eIF3, Rabbit Reticulocytes

RNA-binding component of the eukaryotic translation eIF-3 complex, required for several steps in the initiation of protein synthesis.
Catalog #: P1318

Product Details

Cat # +Size P1318-200
Size 200 μg
Source Rabbit Reticulocytes
Appearance Liquid
Physical Form Description In 20 mM Tris-HCl pH 7.5, 400 mM KCl, 0.1 mM EDTA, 2 mM DTT, and 10 % glycerol
Molecular Weight 650 kDa
Purity by SDS-PAGE ≥99%
Reconstitution Instructions N/A
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans


eIF3 is the largest translation factor and consists of 12 subunits. Complex organization of eIF3 explains its role in almost all steps of translation initiation, including ribosomal subunit anti-association activity, ternary complex recruitment to the 40S subunit, 43S pre-initiation complex loading onto mRNA, and ribosomal scanning.

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