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Product Details
| Cat # +Size | P1318-200 |
|---|---|
| Size | 200 μg |
| Source | Rabbit Reticulocytes |
| Appearance | Liquid |
| Physical Form Description | In 20 mM Tris-HCl pH 7.5, 400 mM KCl, 0.1 mM EDTA, 2 mM DTT, and 10 % glycerol |
| Molecular Weight | 650 kDa |
| Purity by SDS-PAGE | ≥99% |
| Reconstitution Instructions | N/A |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -80°C |
| Shipping Conditions | Dry Ice |
| USAGE | For Research Use Only! Not to be used in humans |
Details
eIF3 is the largest translation factor and consists of 12 subunits. Complex organization of eIF3 explains its role in almost all steps of translation initiation, including ribosomal subunit anti-association activity, ternary complex recruitment to the 40S subunit, 43S pre-initiation complex loading onto mRNA, and ribosomal scanning.
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