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An irreversible inhibitor of ornithine decarboxylase (ODC)
Catalog #: B2651
SKU-Size Size Price Qty
B2651-10 10 mg
B2651-50 50 mg
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Product Details

Alternate Name 2-(Difluoromethyl)ornithine; dfmo; 2,5-diamino-2-(difluoromethyl)pentanoic acid; Difluoromethylornithine
Appearance Off-white powder
CAS # 70052-12-9
Molecular Formula C₆H₁₂F₂N₂O₂
Molecular Weight 182.17
Purity ≥98%
Solubility DMSO
InChi InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12)
PubChem CID 3009
MDL Number MFCD00221766
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Eflornithine (Difluoromethylornithine) is a fluorinated ornithine analog that acts as an irreversible inhibitor of ornithine decarboxylase (ODC). It displays antiangiogenic activity, inhibits carcinogenesis, and induces apoptosis. Eflornithine functions as a chemopreventive and chemotherapeutic agent against neuroblastoma and colorectal cancer. It exhibits cytostatic effects on mammalian cells and tissues.

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