A glutathione peroxidase (GPx) mimetic and a peroxynitrite scavenger
Catalog #: 2169 | abID:

Product Details

Alternate Name 2-Phenyl-1,2-benzisoselenazol-3-(2H)-one
Appearance White to off-white solid
CAS # 60940-34-3
Molecular Formula C₁₃H₉NOSe
Molecular Weight 274.18
Purity ≥99%
Solubility DMSO (~ 5 mg/ml)
InChi InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
PubChem CID 3194
MDL Number MFCD00210937
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


An organo-selenium compound that displays potent antioxidant properties. Acts as a glutathione peroxidase (GPX) mimic as well as being an excellent scavenger of peroxynitrite. The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase (COX) and lipoxygenases at micromolar concentrations. Also acts as a histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1B protein with an IC₅₀ of 5.17 µM.

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