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E6005 (RVT-501)

A selective phosphodiesterase 4 (PDE4) inhibitor
Catalog #: B2263
SKU-Size Size Price Qty
B2263-5 5 mg
$85.00
B2263-25 25 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name Methyl 4-((3-(6,7-dimethoxy-2-(methylamino)quinazolin-4-yl)phenyl)carbamoyl)benzoate; Lotamilast
Appearance White to off-white solid
CAS # 947620-48-6
Molecular Formula C₂₆H₂₄N₄O₅
Molecular Weight 472.5
Purity ≥98% by HPLC
Solubility DMSO
SMILES CNC1=NC2=CC(=C(C=C2C(=N1)C3=CC(=CC=C3)NC(=O)C4=CC=C(C=C4)C(=O)OC)OC)OC
InChi InChI=1S/C26H24N4O5/c1-27-26-29-20-14-22(34-3)21(33-2)13-19(20)23(30-26)17-6-5-7-18(12-17)28-24(31)15-8-10-16(11-9-15)25(32)35-4/h5-14H,1-4H3,(H,28,31)(H,27,29,30)
InChi Key BBTFKAOFCSOZMB-UHFFFAOYSA-N
PubChem CID 24864553
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

E6005 (RVT 501), a selective phosphodiesterase 4 (PDE4) inhibitor, developed for the treatment of atopic dermatitis.


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