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A cysteine protease inhibitor
Catalog #: 1739
SKU-Size Size Price Qty
1739-5 5 mg
1739-25 25 mg
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Product Details

Alternate Name trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane, L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatine, N-(trans-Epoxysuccinyl)-L-leucine 4-guanidinobutylamide
Appearance White crystalline solid
CAS # 66701-25-5
Molecular Formula C₁₅H₂₇N₅O₅
Molecular Weight 357.41
Purity ≥99% by HPLC
Solubility DMSO (25 mg/ml) or H₂O (20 mg/ml)
InChi InChI=1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10+,11+/m0/s1
PubChem CID 439487
MDL Number MFCD00080261
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


E-64 is an irreversible, cell-permeable, potent, and highly selective cysteine protease inhibitor. E-64 will not inhibit serine proteases (except trypsin) like other cysteine protease inhibitors, leupeptin and antipain. A very useful cysteine protease inhibitor for use in in vivo studies because it has a specific inhibition and displays low toxicity.

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