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DuP-697

a potent and selective cyclooxygenase-2 (COX-2) inhibitor
Catalog #: B1517
SKU-Size Size Price Qty
B1517-5 5 mg
$195.00
B1517-25 25 mg
$775.00
More Sizes Get Quote

Product Details

Alternate Name 5-bromo-2-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)-thiophene
Appearance White solid
CAS # 88149-94-4
Molecular Formula C₁₇H₁₂BrFO₂S₂
Molecular Weight 411.3
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml)
SMILES CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC(=C2)Br)C3=CC=C(C=C3)F
InChi InChI=1S/C17H12BrFO2S2/c1-23(20,21)14-8-4-11(5-9-14)15-10-16(18)22-17(15)12-2-6-13(19)7-3-12/h2-10H,1H3
InChi Key AJFTZWGGHJXZOB-UHFFFAOYSA-N
PubChem CID 3177
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

DuP-697 is a potent and selective inhibitor of cyclooxygenase-2 (IC₅₀ values are 10 and 800 nM for COX-2 and COX-1 respectively). Inhibits prostaglandin synthesis and is anti-inflammatory in vivo.


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