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Product Details
| Cat # +Size | 1201-1 |
|---|---|
| Size | 1 ml |
| Alternate Name | Dithiothreitol, DL-1,4-Dithiothreitol, Cleland's reagent, (R*,R*)-1,4-dimercaptobutane-2,3-diol |
| Appearance | Liquid |
| Formulation | 1 M in H₂O |
| CAS # | 3483-12-3 |
| Molecular Formula | C₄H₁₀O₂S₂ |
| Molecular Weight | 154.25 |
| Purity | >99% |
| SMILES | C(C(C(CS)O)O)S |
| InChi | InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1 |
| InChi Key | VHJLVAABSRFDPM-QWWZWVQMSA-N |
| PubChem CID | 446094 |
| MDL Number | MFCD00004877 |
| Handling | Protect from air |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
An excellent reagent for maintaining SH groups in reduced state. DTT quantitatively reduces disulfides. It is effective in sample buffers for reducing protein disulfide bonds prior to SDSPAGE.
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Mohammad RM et al. (2007) Clin. Cancer Res. 13: 2226-2235.
Mohammad, R. M., et al. (2005) Mol. Cancer Ther. 4: 13-21.
Wesche-Soldato, D. E., et al. (2005) Blood 106: 2295-2301.
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