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DTT (Solution)

based on 3 citations in multiple journalsDTT (Solution)34.1 4
A disulfide reducing agent
Catalog #: 1201

Product Details

Cat # +Size 1201-1
Size 1 ml
Alternate Name Dithiothreitol, DL-1,4-Dithiothreitol, Cleland's reagent, (R*,R*)-1,4-dimercaptobutane-2,3-diol
Appearance Liquid
Formulation 1 M in H₂O
CAS # 3483-12-3
Molecular Formula C₄H₁₀O₂S₂
Molecular Weight 154.25
Purity >99%
InChi InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
PubChem CID 446094
MDL Number MFCD00004877
Handling Protect from air
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


An excellent reagent for maintaining SH groups in reduced state. DTT quantitatively reduces disulfides. It is effective in sample buffers for reducing protein disulfide bonds prior to SDSPAGE.

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Mohammad RM et al. (2007) Clin. Cancer Res. 13: 2226-2235.
Mohammad, R. M., et al. (2005) Mol. Cancer Ther. 4: 13-21.
Wesche-Soldato, D. E., et al. (2005) Blood 106: 2295-2301.
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