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DTSSP Crosslinker

A cleavable homobifunctional protein crosslinking reagent
Catalog #: 2337
SKU-Size Size Price Qty
2337-50 50 mg
$98.00
2337-250 250 mg
$385.00
More Sizes Get Quote

Product Details

Alternate Name 1-​[3-​[3-​(2,5-​dioxo-​3-​sulfopyrrolidin-​1-​yl)oxy-​3-​ oxopropyl]disulfanylpropanoyloxy]-​2,5-​dioxopyrrolidine-​3-​sulfonic acid; Sulfo-DSP; DTBSSP
Appearance White to off-white solid
CAS # 81069-02-5
Molecular Formula C₁₄H₁₄O₁₄N₂S₄Na₂
Molecular Weight 608.51
Purity ≥80% by NMR
Solubility H₂O (>6 mg/ml)
SMILES CN(OC(CCSSCCC(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)=O)=O)C(CS(=O)(O[Na])=O)=O
InChi InChI=1S/C13H18N2O13S4.2Na/c1-14(10(17)7-31(21,22)23)27-11(18)2-4-29-30-5-3-12(19)28-15-9(16)6-8(13(15)20)32(24,25)26;;/h8H,2-7H2,1H3,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2
InChi Key LFRKLPYHXPWFCL-UHFFFAOYSA-L
PubChem CID 123933
Handling Protect from air and light
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

KEY FEATURES & APPLICATIONS:• Water-soluble• Has primary amine-reactive N-hydroxysulfosuccinimide (Sulfo-NHS) esters at both ends• Contains cleavable, 8-atom (12 Å) spacer arm• The disulfide bond in the spacer arm is cleavable with reducing agents such as DTT, TCEP, etc.• DTSSP crosslinker is membrane-impermeable, thus enabling cell-surface crosslinking without interfering with intercellular proteins


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