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Product Details
| Alternate Name | 1,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimid in-4-one |
|---|---|
| Appearance | Off-white to white solid |
| CAS # | 284028-90-6 |
| Molecular Formula | C₈H₁₀N₂OS |
| Molecular Weight | 182.24 |
| Purity | ≥98% by HPLC |
| Solubility | H₂O (40 mM) |
| SMILES | CC1=NC(=O)C2=C(N1)CCSC2 |
| InChi | InChI=1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11) |
| InChi Key | HRYKZAKEAVZGJD-UHFFFAOYSA-N |
| PubChem CID | 10219702 |
| MDL Number | MFCD08703132 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A potent, brain-penetrant, and water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor. IC₅₀ values are 0.20 and 0.24 µM for PARP-1 and PARP-2 respectively. Neuroprotective in vitro and in vivo.
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