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DPP4 Inhibitor Screening Kit (Fluorometric)

Simple Assay to Screen DPP4 Inhibitors, HTS
Catalog #: K780
$495.00

Product Details

Cat # +Size K780-100
Size 100 assays
Detection Method Fluorescence (Ex/Em 360/460 nm)
Applications This kit can be used for screening of DPP4 inhibitors.
Kit Components • DPP4 Assay Buffer
• DPP4 Substrate
• DPP4 Enzyme
• DPP4 Inhibitor (Sitagliptin)
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Dipeptidyl peptidase-4 (DPP4) inhibitors have emerged as a new class of oral antidiabetic agents. These inhibitors promote glucose homeostasis by inhibiting degradation of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 by DPP4. Glucagon-like peptide-1 extends the action of insulin while suppressing the release of glucagon. In BioVision’s DPP4 Inhibitor Screening Kit, DPP4 cleaves a substrate to release a quenched fluorescent group (Em/Ex = 360/460 nm). In presence of a DPP4 inhibitor, the cleavage will be inhibited. The kit provides a rapid, simple, sensitive, and reliable test, as well as, suitable for high throughput screening of DPP4 inhibitors. Sitagliptin is included as a control inhibitor to compare the efficacy of the test inhibitors.


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