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Product Details
| Cat # +Size | 1527-5 |
|---|---|
| Size | 5 mg |
| Alternate Name | Adriamycin® hydrochloride, DOX, Hydroxydaunorubicin hydrochloride |
| Appearance | Orange-red powder |
| CAS # | 25316-40-9 |
| Molecular Formula | C₂₇H₂₉NO₁₁ .HCl |
| Molecular Weight | 579.98 |
| Purity | >98% by TLC |
| Solubility | H₂O |
| SMILES | CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl |
| InChi | InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1 |
| InChi Key | MWWSFMDVAYGXBV-RUELKSSGSA-N |
| PubChem CID | 443939 |
| MDL Number | MFCD00077757 |
| Handling | Protect from moisture |
| Storage Conditions | 4°C |
| Shipping Conditions | RT |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Anti-tumor antibiotic. Inhibitor of Reverse transcriptase and RNA Polymerase. Immunosuppressive agent. Highly effective myotoxin that inhibits topoisomerase II. Binds to Nucleic acids, presumably by specific intercalation into the DNA double helix, thereby inhibiting necleic acid synthesis. Induces apoptosis.
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Katoh S-Y et al. J. Biochem 143: 517 - 524.
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