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Doxorubicin.HCl

based on 1 citations in multiple journalsDoxorubicin.HCl14.1 4
Anti-tumor antibiotic
Catalog #: 1527
$95.00

Product Details

Cat # +Size 1527-5
Size 5 mg
Alternate Name Adriamycin® hydrochloride, DOX, Hydroxydaunorubicin hydrochloride
Appearance Orange-red powder
CAS # 25316-40-9
Molecular Formula C₂₇H₂₉NO₁₁ .HCl
Molecular Weight 579.98
Purity >98% by TLC
Solubility H₂O
SMILES CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
InChi InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
InChi Key MWWSFMDVAYGXBV-RUELKSSGSA-N
PubChem CID 443939
MDL Number MFCD00077757
Handling Protect from moisture
Storage Conditions 4°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Anti-tumor antibiotic. Inhibitor of Reverse transcriptase and RNA Polymerase. Immunosuppressive agent. Highly effective myotoxin that inhibits topoisomerase II. Binds to Nucleic acids, presumably by specific intercalation into the DNA double helix, thereby inhibiting necleic acid synthesis. Induces apoptosis.


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Katoh S-Y et al. J. Biochem 143: 517 - 524.
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