Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


A class III antiarrhythmic agent
Catalog #: B1189
SKU-Size Size Price Qty
B1189-5 5 mg
B1189-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 1-(4-Methanesulphonamidophenoxy)-2-[N-(4-methanesulphonamidophenethyl)-N-methylamino]ethane
Appearance White Solid
CAS # 115256-11-6
Molecular Formula C₁₉H₂₇N₃O₅S₂
Molecular Weight 441.56
Purity ≥98% by HPLC
Solubility DMSO (25 mg/ml)
InChi InChI=1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3
PubChem CID 71329
MDL Number MFCD00869707
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Dofetilide is a class III antiarrhythmic agent and inhibits the rapid delayed rectifier K⁺current (IKr) with IC₅₀values of 31.5 nM in guinea pig cardiomyocytes. At higher doses it demonstrates pro-arrhythmic activity in cell models. Therefore, dofetilide has been cautiously used in the treatment of atrial fibrillation, the conversion of flutter to sinus rhythm and in the maintenance of sinus rhythm after conversion.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.