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Docetaxel

An anticancer agent and a microtubule depolymerization inhibitor
Catalog #: 2232
SKU-Size Size Price Qty
2232-10 10 mg
$85.00
2232-50 50 mg
$345.00
More Sizes Get Quote

Product Details

Alternate Name Taxotere; Docefrez
Appearance White solid
CAS # 114977-28-5
Molecular Formula C₄₃H₅₃NO₁₄
Molecular Weight 807.88
Purity ≥99% by HPLC
Solubility DMSO (100 mM) or EtOH (100 mM)
SMILES CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
InChi InChI=1S/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28+,30-,31+,32+,33-,35-,41+,42-,43+/m0/s1
InChi Key ZDZOTLJHXYCWBA-VCVYQWHSSA-N
PubChem CID 148124
MDL Number MFCD00800737
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

An anticancer agent. Docetaxel binds to microtubules reversibly with high affinity and prevents microtubule depolymerization and disassembly in the absence of GTP. Used mainly for the treatment of breast, ovarian, and non-small cell lung cancer.


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