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DNA methylation inhibitor, Dichlone

A DNA methylation inhibitor
Catalog #: 2860
SKU-Size Size Price Qty
2860-500 500 mg
$55.00
2860-1000 1 g
$85.00
More Sizes Get Quote

Product Details

Alternate Name 2,3-Dichloro-1,4-naphthoquinone, Dichlon
Appearance Yellow solid
CAS # 117-80-6
Molecular Formula C₁₀H₄Cl₂O₂
Molecular Weight 227.04
Purity ≥95% by GC
Solubility DMSO or EtOH
SMILES C1=CC=C2C(=C1)C(=O)C(=C(C2=O)Cl)Cl
InChi InChI=1S/C10H4Cl2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H
InChi Key SVPKNMBRVBMTLB-UHFFFAOYSA-N
PubChem CID 8342
MDL Number MFCD00001677
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Dichlone, a popular pesticide and fungicide, acts as a potent DNA methylation inhibitor (EC₅₀ = 460 nM against Dnmt3A/3L catalytic complex). Dichlone efficiently reactivates YFP gene expression in a stable HEK293 cell line by promoter demethylation.


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