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Product Details
| Alternate Name | 2,3-Dichloro-1,4-naphthoquinone, Dichlon |
|---|---|
| Appearance | Yellow solid |
| CAS # | 117-80-6 |
| Molecular Formula | C₁₀H₄Cl₂O₂ |
| Molecular Weight | 227.04 |
| Purity | ≥95% by GC |
| Solubility | DMSO or EtOH |
| SMILES | C1=CC=C2C(=C1)C(=O)C(=C(C2=O)Cl)Cl |
| InChi | InChI=1S/C10H4Cl2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H |
| InChi Key | SVPKNMBRVBMTLB-UHFFFAOYSA-N |
| PubChem CID | 8342 |
| MDL Number | MFCD00001677 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Dichlone, a popular pesticide and fungicide, acts as a potent DNA methylation inhibitor (EC₅₀ = 460 nM against Dnmt3A/3L catalytic complex). Dichlone efficiently reactivates YFP gene expression in a stable HEK293 cell line by promoter demethylation.
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