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DMOG

A hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH) inhibitor
Catalog #: 2216
SKU-Size Size Price Qty
2216-5 5 mg
$60.00
2216-25 25 mg
$225.00
More Sizes Get Quote

Product Details

Alternate Name N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Appearance White solid
CAS # 89464-63-1
Molecular Formula C₆H₉NO₅
Molecular Weight 175.14
Purity ³98% by NMR
Solubility DMSO (100 mM) or H₂O (100 mM)
SMILES COC(=O)CNC(=O)C(=O)OC
InChi InChI=1S/C6H9NO5/c1-11-4(8)3-7-5(9)6(10)12-2/h3H2,1-2H3,(H,7,9)
InChi Key BNJOZDZCRHCODO-UHFFFAOYSA-N
PubChem CID 560326
MDL Number MFCD05865098
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A cell-permeable prolyl 4-hydroxylase (P4H) inhibitor; inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). Increases levels of HIF-1α; promotes cell survival under hypoxic conditions. DMOG posseses neuroprotective effect on NFG deprived cell cultures through preservation of glucose metabolism. DMOG also attenuates myocardial injury in a rabbit ischemia reperfusion model.


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