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Dipyridamole

A phosphodiesterase inhibitor and an antiplatelet agent
Catalog #: B3221
SKU-Size Size Price Qty
B3221-1G 1 g
$75.00
B3221-5G 5 g
$195.00
More Sizes Get Quote

Product Details

Alternate Name NSC 619103; NSC 515776; 2,2’,2”,2”’-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-ethanol
Peptide Sequence N/A
Appearance Yellow to orange crystalline powder
CAS # 58-32-2
Molecular Formula C₂₄H₄₀N₈O₄
Molecular Weight 504.63
Purity ≥98% by HPLC
Solubility >30 mg/ml DMSO
SMILES OCCN(CCO)C1=NC(N2CCCCC2)=C3C(C(N4CCCCC4)=NC(N(CCO)CCO)=N3)=N1
InChi InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2
InChi Key IZEKFCXSFNUWAM-UHFFFAOYSA-N
PubChem CID 3108
MDL Number MFCD00010555
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Dipyridamole is a phosphodiesterase 5A (PDE5A) inhibitor (IC50 = 574 nM) that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. Formulations containing dipyridamole in combination with aspirin have been used to prevent stroke and other cardiovascular events. Apart from the well-known antiplatelet function, DIP may provide potential therapeutic benefits to patients with COVID-19.


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