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Diosmetin

Cytochrome P450 (CYP) inhibitor
Catalog #: B1922

In stock

SKU-Size Size Price Qty
B1922-50 50 mg
$75.00
B1922-250 250 mg
$295.00

Product Details

Alternate Name 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; Disometol
Appearance Crystalline solid
CAS # 520-34-3
Molecular Formula C₁₆H₁₂O₆
Molecular Weight 300.3
Purity ≥98%
Solubility DMSO (~30 mg/ml)
SMILES COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
InChi InChI=1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
InChi Key MBNGWHIJMBWFHU-UHFFFAOYSA-N
PubChem CID 5281612
MDL Number MFCD00017425
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Diosmetin is a natural flavonoid that displays anticancer, antimicrobial, antioxidant, estrogenic and anti-inflammatory activity. It reversibly inhibits cytochrome P450 (CYP) isoforms 1A1 and 1B1 in human liver microsomes with Ki values of 89 and 16 nM, respectively. Diosmetin also activates BMP signaling.


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